Killing from within

Killing from within

Interleukin-10 (IL-10) is considered to be an immunosuppressive cytokine. However, the continuous administration of pegylated IL-10 (PEG-IL10) leads to the rejection of large, firmly established and metastatic syngeneic tumors. PEG-IL10 therapy induces the expansion and activation of intratumoral, tumor antigen-specific CD8(+) T cells, leading to interferon γ (IFNγ)-mediated Th1 like immunity a...

Killing begets killing: evidence from a bug-killing paradigm that initial killing fuels subsequent killing.

Killing appears to perpetuate itself even in the absence of retaliation. This phenomenon may occur in part as a means to justify prior killing and so ease the threat of prior killing. In addition, this effect should arise particularly when a killer perceives similarity to the victims because similarity should exacerbate threat from killing. To examine these ideas, the authors developed a bug-ki...

Killing Tensors and Conformal Killing Tensors from Conformal Killing Vectors

Koutras has proposed some methods to construct reducible proper conformal Killing tensors and Killing tensors (which are, in general, irreducible) when a pair of orthogonal conformal Killing vectors exist in a given space. We give the completely general result demonstrating that this severe restriction of orthogonality is unnecessary. In addition we correct and extend some results concerning Ki...

Killing Tensors from Conformal Killing Ve tors

Killing Tensors from Conformal Killing Vectors

Some years ago Koutras presented a method of constructing a conformal Killing tensor from a pair of orthogonal conformal Killing vectors. When the vector associated with the conformal Killing tensor is a gradient, a Killing tensor (in general irreducible) can then be constructed. In this paper it is shown that the severe restriction of orthogonality is unnecessary and thus it is possible that m...